Perioperative neurocognitive dysfunction
Conditions
Interventions
POCD group:Nil
non-POCD group:Nil
Sponsors
Shanghai Chest Hospital,Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. aged = 65 years old; 2. ASA I-III grade; 3. elective esophageal tumor resection patients.
Exclusion criteria
Exclusion criteria: 1. combined with severe cardiovascular and cerebrovascular disease (near blood pressure, poor blood sugar control); 2. combined with heart, liver, kidney and other important organ dysfunction; 3. preoperative sedative, anti-depressant, anticholinergic and other drugs; 4. Unconsciousness, low intelligence, language communication barriers, and inability to cooperate with the completion of the scale examination; 5. With dementia before surgery (China's revised Mini-Cog simple cognitive assessment scale 5 points, less than 3 points threshold is considered dementia), depression and other neurological disorders; 6. The patient has been included in other studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| brain state index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hematological indicators such as S-100ß, NSE, BFABP; | — |
Countries
China
Contacts
Public ContactMeiying Xu
Shanghai Chest Hospital,Shanghai Jiaotong University
Outcome results
None listed