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Study for the correlation between gut microflora and serum TMAO in chronic kidney disease patients

An attempt to explain the nature of damp-heat accumulation in chronic kidney disease patients based on the correlation between gut microflora and serum TMAO

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800019547
Enrollment
Unknown
Registered
2018-11-18
Start date
2018-12-01
Completion date
Unknown
Last updated
2018-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease

Interventions

Case series:none

Sponsors

Guangdong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-75; 2. Confirmed diagnosis of Stage 5 CKD; 3. Dialysis therapy (peritoneal dialysis, hemodialysis, CRRT and other renal replacement therapy) was not started when the patients were enrolled in the study. 4. Informed and consented.

Exclusion criteria

Exclusion criteria: 1. Having severe uncontrolled primary diseases or malignant tumors of the heart, brain, liver, or hematopoietic system; 2. uncorrectable volume overload, hyperkalemia, acidosis or uremia encephalopathy which requires emergent dialysis; 3. Patients who are severely infected or have already taken antibiotics; 4. Patients who cannot cooperate with the investigation.

Design outcomes

Primary

MeasureTime frame
serum TMAO;gut microflora;—

Countries

China·

Contacts

Public ContactYuchi Wu

Guangdong Provincial Hospital of Chinese Medicine

wuyuchi047@163.com+86 13570361234

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026