Autoimmune Thyroid Diseases
Conditions
Interventions
Sponsors
Affiliated Hospital of Weifang Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Graves disease group (GD group): patients with newly-diagnosed Graves disease. Hashimoto's thyroiditis group (EUHT group): newly-diagnosed Hashimoto's thyroiditis patients with euthyroidism. Hashimoto's thyroiditis with hypothyroidism group (Hypo-HT group): newly-diagnosed Hashimoto's thyroiditis patients with hypothyroidism or subclinical hypothyroidism; Hypothyroidism group(Hypo-NC): newly-diagnosed patients with hypothyroidism or subclinical hypothyroidism. Normal control group (NC group): 1. People with normal thyroid function and negative thyroid-antibodies; 2. aged 18 to 75 years old; 3. Did not receive any anti-thyroid drug treatment; 4. Understand the purpose of clinical trials and voluntarily participate in and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Thyroid tumors, high thyroid function adenomas, nodular thyroiditis, subacute thyroiditis and other thyroid or pituitary, hypothalamic diseases; 2. other endocrine and other autoimmune diseases; 3. with severe physical diseases Patients; 4. taking drugs affecting thyroid function or immune system recently; 5. pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum Sestrin2; | — |
Secondary
| Measure | Time frame |
|---|---|
| FT3;FT4;A-TSHR;TPO-Ab;TG-Ab;TSH; | — |
Countries
China
Contacts
Public ContactSun Xiaodong
Affiliated Hospital of Weifang Medical University
Outcome results
None listed