HPV infection
Conditions
Interventions
Group 1:CTL Injection (Autogenous Cells)
Group 2:CTL Injection (Umbilical Cord Blood Cells)
Group 3:HPV-DC vaccination
Sponsors
Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine
Eligibility
Sex/Gender
Female
Age
30 Years to 55 Years
Inclusion criteria
Inclusion criteria: 1. HPV test should be positive ,Conforming to diagnosis of cervical high risk HPV infection; 2. Aged 30 to 55 years; 3. Cervix high-risk type HPV HC2 inspecting at least 1 time for positive in the latest 6 months; 4. Heart, lung, liver and kidney function well; 5. signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Negative HPV DNA test; 2. Genital tract inflammation (gonorrhea, chlamydia, Candida vaginitis, Trichomonas vaginitis, Bacterial vaginal disease Etc.); 3. A weakened immune system (Radiation andchemotherapy after, AIDS, SLE Etc.); 4. Patient with severe autoimmune disease; 5. Allergic to cytokines; 6. Lactation and pregnancy; 7. Patient with a serious infectious disease; 8. With cardiovascular, cerebrovascular, liver, kidney andhematopoietic system andother serious primary diseases andpsychiatric patients; 9. Nearly three months treatment of HPV infection measures; 10. Nearly three months in other clinical trials; 11. History of organ transplantation; 12. mental illness and Cognitive impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| negative conversion rate of HPV;HC2 test;HPV Ag test;HPV Ab test;CD3+CD8+CD28+ T cells; | — |
Countries
China
Contacts
Public ContactZhao Zhenlin
Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine
Outcome results
None listed