Chronic osteomyelitis
Conditions
Interventions
Gold Standard:Positive histopathological examination or positive bacterial culture of
sequencing
Sponsors
Nanfang Hospital, Southern Medical University
Eligibility
Sex/Gender
All
Age
15 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Patients with chronic osteomyelitis of long bone of lower limbs (femur or tibia), and antibiotics were discontinued for more than two weeks; 2) Surgical indications (infected marrow cavity or cortex, dead bones, dead cavities, sinus drainage pus, sufficient new bone to form a capsule or non-union); 3) Aged 15 to 65 years old; 4) Single site infection.
Exclusion criteria
Exclusion criteria: 1) patients had lower extremity vascular disease which could not be resolved by surgery; 2) there are contraindications for operation: heart disease and abnormal pulmonary function; 3) poor nutritional status, moderate and severe anemia, hypoalbuminemia (albumin below 30g/L); 4) the duration of onset of infection is less than 3 months; 5) chronic osteomyelitis of non long bone of the lower limb.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive rate of microorganism culture;positive rate of next generation sequencing; | — |
Countries
China
Contacts
Public ContactLiu Shiluan
Southern Medical University Nanfang Hospital
Outcome results
None listed