Effects of different sedation drugs on postoperative renal function of patients undergoing crdiopulmonry bypss heart surgery and its relationship with glycocalyx

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800019481

Enrollment

Unknown

Registered

2018-11-13

Start date

2018-11-01

Completion date

Unknown

Last updated

2018-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute kidney injury

Interventions

Group 1:sevoflurane

Group 2:propofol

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) ASA grade I to III; (2) aged 18 to 65 years; (3) elective patients who underwent simple two or three valve replacement.

Exclusion criteria

Exclusion criteria: (1) patients with coronary heart disease; diabetic patients; active infective endocarditis; (2) severe liver and kidney dysfunction before surgery; patients with myocardial infarction within four weeks, or patients with propofol allergy; (3) Patients with secondary thoracotomy and cardiopulmonary resuscitation during experimental observation;

Design outcomes

Primary

Measure	Time frame
neutrophil gelatinase-associated lipocalin;Plasma heparin sulfate;	—

Countries

China

Contacts

Public ContactZou Xiaohua

The Affiliated Hospital of Guizhou Medical University

562931613@qq.com+86 13809416036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026