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The effect and mechanism of fluoxetine on the automatic regulation of cerebral blood flow for ischemic stroke

The effect and mechanism of fluoxetine on the automatic regulation of cerebral blood flow for ischemic stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019467
Enrollment
Unknown
Registered
2018-11-12
Start date
2019-01-01
Completion date
Unknown
Last updated
2018-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke

Interventions

Control group:Conventional therapy
Fluoxetine group:Fluoxetine (20mg/day, for 90 days), and conventional therapy

Sponsors

Shenzhen People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. According to the world health organization's diagnostic criteria for acute cerebral infarction, cerebral infarction patients with cerebral hemispheric infarction whose responsible vessels were identified by cranial CT or cranial MRI; 2. initial occurrence of ischemic stroke; 3. the onset time is within 3 days; 4. aged 30-80 years; 5. the patient or family member signs the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with hemorrhagic cerebral infarction; 2. Coma patients; 3. Patients with massive cerebral infarction; 4. Patients with poor coordination of transcranial doppler ultrasonography; 5. Patients who are participating in or have participated in other clinical trials within 3 months.

Design outcomes

Primary

MeasureTime frame
Automatic regulation of cerebral blood flow;—

Countries

China

Contacts

Public ContactHe Yitao

Shenzhen People's Hospital

heyitaovv@126.com+86 13590419894

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026