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Study for the effect and mechanism of moxibustion on immune cells in ovarian cancer patients with II degree leucopenia after chemotherapy

Study for the effect and mechanism of moxibustion on immune cells in ovarian cancer patients with II degree leucopenia after chemotherapy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019462
Enrollment
Unknown
Registered
2018-11-06
Start date
2018-11-15
Completion date
Unknown
Last updated
2018-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

leucopenia after chemotherapy

Interventions

Group 2:inject rhG-CSF
Group 3:none

Sponsors

The Third Hospital Affiliated to Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
50 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Ovarian epithelial serous adenocarcinoma or mucinous adenocarcinoma confirmed by histopathology or cytopathology, with stages II-III; 2. Chemotherapy regimen: paclitaxel 175 mg/m^2, intravenous drip > 3 h; carboplatin AUC 5-6 intravenous drip > 1 h; repeated every 3 weeks; 3. Aged 50 to 65 years old; 4. the physical condition of the subjects is acceptable, and the Karnofsky score is more than 80 points; 5. the degree of bone marrow suppression: Grade II: white blood cells (2 ~ 2.9) x 10^9/L; 6. the subjects agreed well and agreed to sign informed consent.

Exclusion criteria

Exclusion criteria: 1. leucopenia caused by other causes; 2. pregnant and intentional pregnancy or lactation women; 3. combined with severe heart, liver, spleen, lung, kidney, bone and other important organ damage; 4. those with cognitive impairment or severe mental illness; 5. patients with hematological diseases; 6. patients with autoimmune diseases; 7. those with severe infection or chronic infectious diseases; 8. those who use other myelosuppressive drugs or leukocytosis drugs during the treatment; 9. those who had received moxibustion treatment within 1 months before participating in the study; 10. participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Immune Repertoire sequencing;

Secondary

MeasureTime frame
Lymphocyte Subgroup Classification;complete blood count;

Countries

China

Contacts

Public ContactJinchang Huang

Beijing University of Chinese Medicine

zryhhuang@163.com+86 13910801918

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026