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Investigation of effects of supplementation of DHA-fortified milk powder during pregnancy and lactation on the health of mothers and infants: a randomized clinical trial

Investigation of effects of supplementation of DHA-fortified milk powder during pregnancy and lactation on the health of mothers and the content of DHA in breast milk: a randomized clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019461
Enrollment
Unknown
Registered
2018-11-12
Start date
2018-11-16
Completion date
Unknown
Last updated
2018-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

level of DHA in breast milk

Interventions

Group of fortified milk powder during pregnancy and lactation:DHA fortifed milk powder
Group of fortified milk powder during pregnancy:DHA fortifed milk powder and ordinary milk powder
Group of ordinary milk powder:ordinary milk powder

Sponsors

Peking University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1) Pregnant women aged 20 to 40 years; 2) At 28 weeks of gestation; 3) Plan to breastfeed infants and continue breastfeeding to over 4 months; 4) Singleton pregnancy.

Exclusion criteria

Exclusion criteria: 1) Pregnant women who are lactose intolerance. 2) Pregnant women who are allergic to milk protein. 3) Pregnant women with liver and kidney function damage; 4) Any other reasons lead to milk powder intolerance. 5) Those who are using DHA fortified foods and DHA dietary supplements; 6) With metabolic diseases, including gestational diabetes, hypothyroidism; 4) With physical disability and infectious diseases (such as hepatitis B, HIV);

Design outcomes

Primary

MeasureTime frame
level of DHA in breast milk;

Secondary

MeasureTime frame
fatty acids in the plasma of pregnant and lactating women;fatty acids in the stool of pregnant and lactating women;fatty acids in cord blood;intestinal flora of pregnant and lactating women;psychological health of pregnant and lactating women;intestinal flora of infants;fatty acids in the stool of infants;neurodevelopment of infants;length of infants;weight of infants;head circumference of infants;fatty acids in breast milk;immunologic factors in plasma;

Countries

China

Contacts

Public ContactYumei Zhang

Peking University

zhangyumei@bjmu.edu.cn+86 13426134251

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026