Spinal Deformity
Conditions
Interventions
A:Degenerative Spinal Deformity
Sponsors
The First Affiliated Hospital of Army Medical University, PLA
Eligibility
Sex/Gender
All
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Voluntarily participate in the test and sign the informed consent; 2. Age > 45 years old male and female; 3. At the same time,patients whose imaging parameters satisfy the coronal Cobb>10 degree and/or sagittal SVA > 5cm are included in degenerative spinal deformity group ("deformed group" for short); 4. The rest of the patients who do not meet the diagnostic criteria for degenerative spinal deformity are included in the normal control group ("control group"for short).
Exclusion criteria
Exclusion criteria: 1. Patients with cauda equina syndrome; 2. Patients with other lumbar conditions that will, in the opinion of the investigator, interfere with clinical outcomes (e.g. fresh spinal fractures, mandatory spondylitis, spinal tuberculosis, spinal infections, spinal tumors, spinal surgery history); 3. Systemic infection or other diseases that threaten life and seriously affect the quality of life; 4. Patients with cardiac pacemakers and stents, electromagnetic cochlea, aneurysm clips and other implants in the body that are not suitable for MRI examination; 5. Recent history (less than 3 years) of chemical substance dependency or significant psychosocial disturbance, which may impact the outcome or study participation; 6. Participation in a clinical trial of investigational drug or device within the past 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximal Isometric Strength;Peak Torque(PT);Cross-sectional area (CSA);Muscle Fat Infiltration (MFI);Oswestry Disability Index (ODI);Mos 36-item Short Form Health Survey (SF-36); | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to Fatigue (TTF);Visual Analogue Scale/Score (VAS);Mean Signal Intensity (MSI);Roland-Morris Disability (RMD);Spinal Pelvic Parameters; | — |
Countries
China
Contacts
Public ContactLuo Fei
The First Affiliated Hospital of Army Medical University, PLA
Outcome results
None listed