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Effects of intraocular injection of different anti-VEGF drugs on inflammatory factors in aqueous humor of patients with diabetic retinopathy

Effects of intraocular injection of different anti-VEGF drugs on inflammatory factors in aqueous humor of patients with diabetic retinopathy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800019455
Enrollment
Unknown
Registered
2018-11-12
Start date
2018-11-12
Completion date
Unknown
Last updated
2019-03-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic retinopathy

Interventions

Group 2:intravitreal conbercept(IVC) injection
Group 1:intravitreal ranibizumab(IVR) injection

Sponsors

The Fourth Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 100 Years

Inclusion criteria

Inclusion criteria: Patients who had PPV because of PDR, patients who had intravitreal conbercept(IVC) injection and patients who had intravitreal ranibizumab(IVR) injection 3-7d before surgery (rather than other anti-VEGF drgs), and patients who were followed up for at least 3 months.

Exclusion criteria

Exclusion criteria: Previous vitreoretinal surgery, patients with IVC injectiong>1wk before the surgery, neovascular glaucoma, known coagulation abnormalities or current use of anticoagulant or antiplatelet therapy that had high bleeding risk, and additional vitreretinal pathologies such as retinal detachment, uveities, and retinal artery or vein occlusion.

Design outcomes

Primary

MeasureTime frame
VEGFR2;

Countries

China

Contacts

Public ContactMa Liwei

The Fourth Hospital of China Medical University

sdtazhuweijie@163.com+86 18900913588

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026