Gastroesophageal reflux disease related Laryngologic reflux disease
Conditions
Interventions
Group 1:Omeprazole Enteric-coated Tablets+Tiaoganlipi prescription granules
Group 2:Omeprazole Enteric-coated Tablets+Tiaoganlipi prescription granules analogue
Sponsors
Beijing Hospital of TCM Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. meet the GERD diagnostic standard for Laryngology and reflux disease. RSI>13 and/or RFS>7?, 24 hours, throat acid reflux event was more than 3 times or throat throat pH <4 total time was more than 1%. 2. Aged 18 to 65 years old male and female; 3. Informed consent, volunteers.
Exclusion criteria
Exclusion criteria: (1) operation history of stomach, esophagus and duodenum; (2) suffering from Zhuo AI syndrome and primary esophageal motility disease; (3) suspected or confirmed malignant diseases or any early warning symptoms; (4) PPI or H2 receptor blockers were used in the first 1 weeks; (5) severe primary heart, liver, lung, kidney, pancreas, liver, or severe diseases affecting their survival; (6) Persons with disabilities prescribed by law (blind, deaf, dumb, mental retardation, mental retardation, physical disability); (7) there is a history of alcohol or drug abuse; (8) Allergic constitution, such as those who have a history of allergy to two or more drugs or foods, or are known to be allergic to the ingredients of this drug; (9) poor compliance or failure to cooperate; (10) pregnant, pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| refiux symptom index;reflux finding score; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM syndrome score;24 hour esophageal PH monitoring index; | — |
Countries
China
Contacts
Public ContactLin Tao
Beijing Hospital of TCM Affiliated to Capital Medical University
Outcome results
None listed