Digestive diseases linked to HP infection
Conditions
Interventions
Group 1:14 days' regimen of the combined treatment of bismuth
Group 2:14 days' regimen of the combined treatment of bismuth + Qin-Re-Hua-Shi method
Sponsors
Peking Univeisity First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Chronic gastritis or inactive ulcer were diagnosed by endoscopy and pathological examination. 2. HP infection was diagnosed by urea 13C breath test, endoscopic rapid urease test or stool antigen test. 3. Uneradicated treatment, no antibiotics within one month, no acid suppressant and gastric mucosal protectant within 2 weeks; 4. The syndrome differentiation of TCM is spleen and stomach dampness heat syndrome, and the diagnostic criteria of spleen and stomach dampness heat syndrome refer to the consensus opinion of TCM diagnosis and treatment of chronic gastritis (2017); 5. Aged 18-70 years male and female; 6. The subjects (or legal representatives) voluntarily consented and signed informed consent and were able to follow the research program during the study.
Exclusion criteria
Exclusion criteria: 1. Endoscopic examination showed active ulcer; 2. Having a history of gastric surgery; 3. Long-term administration of non-steroidal anti-inflammatory drugs and PPI,H2RA, mucosal protectants; 4. Severe diseases, such as severe liver disease, heart disease, kidney disease, nausea, tumor and alcoholism, which were evaluated by the impact study; 5. Allergy to the drugs used in this study; 6. Having participated in other drug clinical studies within 3 months before participating in this project; 7. Patients could not express their subjective feelings correctly and could not cooperate with each other; 8. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The eradication rate of H.pylori; | — |
Secondary
| Measure | Time frame |
|---|---|
| Score of symptoms; | — |
Countries
China
Contacts
Public ContactHUI YE
Peking Univeisity First Hospital
Outcome results
None listed