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A randomized double-blind controlled trial for low-dose dexmetidine and lidocaine in the treatment of post-craniotomy pain in children

A randomized double-blind controlled trial for low-dose dexmetidine and lidocaine in the treatment of post-craniotomy pain in children

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019411
Enrollment
Unknown
Registered
2018-11-10
Start date
2018-12-01
Completion date
Unknown
Last updated
2019-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain in pediatric neurosurgery

Interventions

Group 1:Intravenous injection of dexmetidine
Group 2:Intravenous injection of lidocaine
Group 3:Intravenous injection of saline

Sponsors

Beijing Tiantan Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 12 Years

Inclusion criteria

Inclusion criteria: 1) Aged 1-12 years old; 2) ASA 1-3; 3) Children with craniotomy; 4) Informed consent signed by the patient or his guardian.

Exclusion criteria

Exclusion criteria: 1) Psychological disorders; 2) Airway abnormality; 3) Children who cannot remove tracheal incubation after operation; 4) Children with hematoma or severe cerebral edema who require a second operation 3 days after operation; 5) Patients participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
postoperative pain score;use of analgesics;safety evaluation of analgesic pump;

Secondary

MeasureTime frame
general situation of children;postoperative complications ;

Countries

China

Contacts

Public ContactXu Jin

Beijing Tiantan Hospital, Capital Medical University

xiehe2000@163.com+86 13693336261

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026