Thyroid Nodule diseases
Conditions
Interventions
Group 1:Volatile anesthesia induction
Group 2:Total intravenous anesthesia induction
Group 3:intravenous-volatile combined anesthesia induction
Sponsors
Zhongnan Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Male and female patients aged 18–80 years, planned for thyroid surgery under general anesthesia, ASA grades I or II, BMI 18.5 to 24.9.
Exclusion criteria
Exclusion criteria: Patients with cardiac insufficiency, respiratory insufficiency, liver or kidney dysfunction; with neuromuscular or neurological disorders; pre-operative hoarseness, recent tone change, coughing when drinking or eating, or no such clinical symptoms but pre-operative laryngoscopy shows vocal cord fixation or movement disorder which suggests involvement or injury of recurrent laryngeal nerve; difficult airway through pre-operative assessment; if the patient is taking drugs that may affect neuromuscular conduction, such as antiepileptic drugs, antiarrhythmic drugs or magnesium agents.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EMG signal;Intubation condition;Mean arterial pressure;Heart rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| BMI;BIS; | — |
Countries
China
Contacts
Public ContactPeng Mian
Zhongnan Hospital of Wuhan University
Outcome results
None listed