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A randomized, double-blinded, crossover controlled trial for the health effect of traffic related air pollution (TRAP) to healthy young adults

A randomized, double-blinded, crossover controlled trial for the health effect of traffic related air pollution (TRAP) to healthy young adults

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019360
Enrollment
Unknown
Registered
2018-11-07
Start date
2018-11-15
Completion date
Unknown
Last updated
2018-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

One:Powered air purified respirator with sham filter
Two:Powered air purified respirator with PM filter
Three:Powered air purified respirator with PM and VOCs filter

Sponsors

Chinese Research Academy of Environmental Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 30 Years

Inclusion criteria

Inclusion criteria: Aged between 20 and 30 years healthy adults.

Exclusion criteria

Exclusion criteria: 1. current smoker or/and alcoholics or/and drug abuse; 2. have a family history of genetic disease; 3. any of the following illnesses: chronic respiratory, cardiovascular, liver, renal, hematological disease, diabetes mellitus, serious gastrointestinal disorders and other systemic diseases.

Design outcomes

Primary

MeasureTime frame
Fractional Exhaled Nitrogen Oxides;FEV1;FEV;FEV1%;PEF;Standard deviation of NN intervals (SDNN);Root mean square of successive differences (RMSSD);Cytokines such as IL-6, IFN?, TNFa;8-OHdG;OH-PAHs;—

Countries

China

Contacts

Public ContactBin Han

Chinese Research Academy of Environmental Sciences

hanbin@craes.org.cn+86 18614092769

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026