Head and Neck Cancer
Conditions
Interventions
Case series:MINIPDX
Sponsors
First Affiliated Hospital, College of medicine, Zhejiang University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Pathological histological diagnosis of head and neck cancer(required neoadjuvant therapy); 2. The patient should live without any other cancers according to the clinical examination; 3. The patients could provide biopsy,fresh tumor tissue or pleuroperitoneal fluids samples; 4. Objective tumors that meet RECIST 1.1 criteria and can be evaluated by CT/MRI; 5. KPS score = 60, expected survival time = 3 months; Comprehensive assessment of patients who can tolerate chemotherapy and targeted therapy; 6. The patient voluntarily signed the informed consent form, with good compliance, willing active treatment and follow-up.
Exclusion criteria
Exclusion criteria: 1. Unplanned reoperation after surgery; 2. The patient was confirmed to living with other cancers which may cause interferences to this resaerch; 3. KPS score = 60 points or blood biochemical tests suggest that patients are not suitable for continuing chemotherapy or chemotherapy has been delayed; 4. Cannot or refuse to collect tumor samples; 5. Refused to receive treatment plans or follow-up plans.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective response rate;Five-year survival rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-Free-Surviva;Overall survival; | — |
Countries
China
Contacts
Public ContactYulong Zheng
First Affiliated Hospital, College of Medicine, Zhejiang University
Outcome results
None listed