Digestive diseases linked to HP infection
Conditions
Interventions
Group 1:Bismuth-containing quadruple
Group 2:Jinghuaweikang Quadruple therapy
Group 3:Jinghuaweikang Quadruple therapy 14days and Jinghuaweikang continuation of treatment 14 days
Group 4:Jinghuaweikang and Bismuth-containing quadruple 10days
Sponsors
Peking Univeisity First Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years; 2. The number of failed normative eradication treatment is one to three times in past two years,discontinuation time distance from final eradication treatment is two to three months at least ,in the previous treatments Furazolidone was not used; 3. In the past two years they were diagnosed with chronic gastritis through the gastroscopy; 4. The breath test is positive two weeks before treatment.
Exclusion criteria
Exclusion criteria: 1. Long periods of taking antibiotics, bismuth agent, H2RA, PPI and NSAIDs four weeks before treatment; 2. History of peripheral neuropathy; 3. Pregnant or lactating; 4. Allergic to drugs applied this project; 5. Enrolled by other clinical trials within 3 months; 6. Subject who have serious diseases that affect this project evaluation can't express feelings correctly and cooperation; 7. Severe lung disease,heavy smoking,lower lung function in people.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The eradication rate of H.pylori; | — |
Secondary
| Measure | Time frame |
|---|---|
| Score of symptoms;Relapse of H.pylori infection; | — |
Countries
China
Contacts
Public ContactXUEZHI ZHANG
Peking Univeisity First Hospital
Outcome results
None listed