A randomized controlled trial for mineralized collagen modified polymethylmethacrylate bone cement in the treatment of primary total knee arthroplasty

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800019316

Enrollment

Unknown

Registered

2018-11-05

Start date

2018-11-15

Completion date

Unknown

Last updated

2018-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Group 1:MC-PMMA

Group 2:PMMA

Eligibility

Sex/Gender

All

Age

50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. aged 60-80 years; 2. diagnosis of knee osteoarthritis; 3. bilateral total knee arthroplasty.

Exclusion criteria

Exclusion criteria: 1. complicated with severe osteoporosis; 3. accepted TKA for rheumatoid arthritis of hemophilic arthritis; 4. contraindication for bilateral TKA; 5. allergy to PMMA or MC.

Design outcomes

Primary

Measure	Time frame
radiolucent line;implant loosening;	—

Secondary

Measure	Time frame
hemoglobin;CRP;KSS;	—

Countries

China

Contacts

Public ContactXisheng Weng

Peking Union Medical College Hospital

xshweng@medmail.com.cn+86 13366200018

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026