Skip to content

A randomised controlled phase III study for comparing HAA and DA regimen as induction therapy for adult acute myeloid leukemia

A randomised controlled phase III study for comparing HAA and DA regimen as induction therapy for adult acute myeloid leukemia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019306
Enrollment
Unknown
Registered
2018-11-04
Start date
2018-11-20
Completion date
Unknown
Last updated
2018-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute myeloid leukemia

Interventions

Group 1:HAA regimen
Group 2:DA regime

Sponsors

the First Affliated Hospital,College of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) newly diagnosed AML patients by WHO (except APL); 2) Aged 15-60 years old; 3) the ECOG score was 0-2 at the time of inclusion; 4) Liver and kidney function: blood bilirubin 50%; 6) the expected survival period is more than 3 months; 7) informed consent signed by a patient or family member.

Exclusion criteria

Exclusion criteria: 1) Acute promyelocytic leukemia; 2) there are other malignant tumors in the past 5 years; 3) HIV positive; 4) Other serious diseases that may limit patients'participation in the trial (e.g. advanced infections, uncontrollable diabetes, severe cardiac insufficiency or angina pectoris, etc.); 5) systemic condition is not suitable for chemotherapy; 6) pregnant or lactating women; 7) unable to understand or follow the research plan; 8) secondary to MPN or treatment related AML

Design outcomes

Secondary

MeasureTime frame
overall survival;Event-free survival;safety;relapse-free survival;

Primary

MeasureTime frame
compete remission;

Countries

China

Contacts

Public ContactJie Jin

the First Affliated Hospital,College of Medicine, Zhejiang University

jiej0503@163.com+86 13505716779

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026