acute myeloid leukemia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) newly diagnosed AML patients by WHO (except APL); 2) Aged 15-60 years old; 3) the ECOG score was 0-2 at the time of inclusion; 4) Liver and kidney function: blood bilirubin 50%; 6) the expected survival period is more than 3 months; 7) informed consent signed by a patient or family member.
Exclusion criteria
Exclusion criteria: 1) Acute promyelocytic leukemia; 2) there are other malignant tumors in the past 5 years; 3) HIV positive; 4) Other serious diseases that may limit patients'participation in the trial (e.g. advanced infections, uncontrollable diabetes, severe cardiac insufficiency or angina pectoris, etc.); 5) systemic condition is not suitable for chemotherapy; 6) pregnant or lactating women; 7) unable to understand or follow the research plan; 8) secondary to MPN or treatment related AML
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| overall survival;Event-free survival;safety;relapse-free survival; | — |
Primary
| Measure | Time frame |
|---|---|
| compete remission; | — |
Countries
China
Contacts
the First Affliated Hospital,College of Medicine, Zhejiang University