chronic rhinosinusitis
Conditions
Interventions
chronic rhinosiusitis with nasal polyps group:medical therapy with glucocorticoid
Sponsors
Beijing Tongren Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: The diagnostic criteria were based on the Chinese Diagnostic and Therapeutic Guidelines for Chronic Rhinosinusitis (Kunming, 2012) and EPOS 2012 diagnostic criteria. All enrolled patients were screened by uniform inclusion and exclusion criteria. At the same time, the study subjects did not use systemic or topical glucocorticoids for nearly one month.
Exclusion criteria
Exclusion criteria: 1. patients with CF, Kartgener Disease, invasive and noninvasive fungal sinusitis, neoplasm,and immunodeficiency; 2. patients with acute airway infection in recent one month; 3. patients with allergic rhinitis or/and asthma were excluded. Diagnosis of allergic rhinitis According to the diagnostic criteria of ARIA2008, the diagnosis of asthma is based on GINA standards.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sphingosine-1 phosphate;Signal pathway of Sphingosine-1 phosphate; | — |
Countries
China
Contacts
Public ContactBing Zhou
Beijing Tongren Hospital, Capital Medical University
Outcome results
None listed