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Effects of different plasma target concentrations infusion of propofol on ventricular repolarization in patients with type 2 diabetes mellitus and its mechanism

Effects of different plasma target concentrations infusion of propofol on ventricular repolarization in patients with type 2 diabetes mellitus and its mechanism

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800019278
Enrollment
Unknown
Registered
2018-11-02
Start date
2018-12-10
Completion date
Unknown
Last updated
2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes mellitus

Interventions

Type 2 diabetes mellitus group:Propofol

Sponsors

Guizhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with type 2 diabetes mellitus (type 2 diabetes mellitus with a history of two years or more than two years and regularly use hypoglycemic drugs or HbA1c=6.5% or fasting blood glucose=7.0mmol/L) and non-diabetic patients, aged 25 to 65 years old, ASAI ~ III .

Exclusion criteria

Exclusion criteria: (1) Patients with cardiac surgery and pregnant women; (2) Patients with preoperative cardiopulmonary function, liver and kidney function or electrolyte abnormalities; (3) ECG patients with obvious arrhythmia, including atrial fibrillation, atrioventricular block, etc, or heart rate Corrected QT interval (QTc interval) male=450 ms, female=460 ms; (4) Using drugs known to inhibit fast-acting delayed rectifier potassium current (IKr) and prolonging QT interval (anti-arrhythmia drug, ß Receptor blockers, antidepressants, phenothiazines, etc).

Design outcomes

Primary

MeasureTime frame
ECG parameters;—

Countries

China

Contacts

Public ContactHong Gao

Guizhou Medical University

2169617@qq.com+86 13037810201

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026