Rheumatoid Arthritis
Conditions
Interventions
Sponsors
Shanghai Traditional Medicine University Affiliated Guanghua Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: The consent to participation was obtained from patients who were clearly diagnosed as rheumatoid arthritis andeither: 1) L1-L4 or hip T value =-2.5 in BMD measurement plus obvious low back pain, night convulsions and limited life function symptoms, or 2) L1-L4 or hip joint T value = -1.5, = -2.5 in BMD measurement plus obvious low back pain, night convulsions and limited life function symptoms, with previous one or more fracture history.
Exclusion criteria
Exclusion criteria: (1) severe primary diseases in cardiovascular, cerebrovascular, liver, kidney and hematopoietic system, consumptive chronic diseases, or mental illness; (2) hypercalcemia, fresh fractures, liver or kidney dysfunction, thyroid-related diseases (such as hypothyroidism, hyperthyroidism), or malignant tumors; (3) other joint-involving rheumatic diseases, such as systemic lupus erythematosus, dermatomyositis, Sjogren's syndrome, ankylosing spondylitis, gout, etc; (4) allergy to the test drug zoledronate, or history of other allergies; (5) pregnancy, breastfeeding, or planning to become pregnant in the near future; (6) currently participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CRP;ESR;BMD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Morning time;Patient and doctor evaluation; | — |
Countries
China
Contacts
Public ContactXiao Lianbo
Shanghai Traditional Medicine University Affiliated Guanghua Hospital
Outcome results
None listed