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Lidocaine as an effective intravenous adjuvant to ketamine in children requiring procedural sedation and analgesia

Lidocaine as an effective intravenous adjuvant to ketamine in children requiring procedural sedation and analgesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019274
Enrollment
Unknown
Registered
2018-11-02
Start date
2013-03-01
Completion date
Unknown
Last updated
2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery anesthesia

Interventions

Group 1:injection with ketamine
Group 2:injection with ketamine and lidocaine

Sponsors

Jian-ping Zhang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 12 Years

Inclusion criteria

Inclusion criteria: Children (n = 586) who underwent an operation in Guizhou Provincial Peoples Hospital and Guizhou University Peoples Hospital from March 2013 to December 2015 were selected, including 338 cases receiving hernia repair, 140 cases receiving cleft lip and palate repair and 108 cases receiving appendectomy. The operation time was 15 to 100 min with a mean time of 55.26+/-4.45 min. There were 478 males and 108 females aged 2 ~ 12 years (mean age of 6.35+/-2.32 years) and weighing 9.13 ~ 55.42 kg (mean weight of 22.03 ± 6.28 kg).

Exclusion criteria

Exclusion criteria: Pediatric patients who had cardiovascular and respiratory diseases or patients who had controindiction of ketamine and lidocaine are excluded.

Design outcomes

Primary

MeasureTime frame
blood pressure;heart rate;respiratory rate;blood oxygen saturation;

Countries

China

Contacts

Public ContactJian-ping Zhang

Department of Anesthesiology, Guizhou Provincial People's Hospital

profzhangjianping@126.com+86 18608518156

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026