Pulmonary complications
Conditions
Interventions
Group 1:Deep neuromuscle-blocking laparoscopic surgery with conventional ventilation
Group 2:Deep neuromuscle-blocking laparoscopic surgery with PLVS
Sponsors
Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. aged at least 65 years old, BMI 18.5-30kg/m2; 2. patients undergoing elective laparoscopic abdominal surgery; 3. estimated mechanical ventilation time is greater than 2 hours; 4. Sign the research informed consent form; 5. SpO2 = 95% when inhaling air.
Exclusion criteria
Exclusion criteria: 1. ASA anesthesia grade = 4; 2. body mass index = 30kg / m2; 3. Within 1 months, there were acute respiratory failure, pneumonia, ALI/ARDS, asthma attack, etc. or a history of mechanical ventilation greater than 1 hour within 2 weeks before surgery; 4. can not communicate before surgery because of coma, severe mental retardation, language or hearing impairment; 5. existing hemodynamic instability, sepsis or septic shock; 6. patients have schizophrenia, epilepsy, Parkinson's disease, progressive neuromuscular diseases such as myasthenia gravis; 7. patients with severe COPD (required assisted ventilation / oxygen therapy / repeated acute attacks requiring systemic hormonal therapy) or patients with pulmonary bullae; 8. severe heart, liver, kidney disease (NYHA = III / suspicious malignant arrhythmia / acute coronary syndrome / uremia / hepatic encephalopathy, etc.); 9. involved in other clinical studies or refused to participate in the research; 10. high blood pressure patients whose blood pressure is not properly controlled; hypoproteinemia; 11. with infection history in past 1 week before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PPCs; | — |
Countries
China
Contacts
Public ContactQingguo Zhang
Department of Anesthesiology, Zhujiang Hospital, Southern Medical University
Outcome results
None listed