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The effect of general anesthesia combined with regional block for postoperative pain and cognitive function after bariatric surgery

The effect of general anesthesia combined with regional block for postoperative pain and cognitive function after bariatric surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019236
Enrollment
Unknown
Registered
2018-11-01
Start date
2018-11-02
Completion date
Unknown
Last updated
2021-09-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity

Interventions

Group GA:combined inhalation and intravenous anesthesia
Group GA+TAP:combined inhalation and intravenous anesthesia + bilateral transverse abdominis plane block
Group GA+QLB:combined inhalation and intravenous anesthesia + bilateral quadratus lumborum block

Sponsors

The Anesthesiology and Perioperative Medical Department of the Second Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) ASA I, II; (2) Aged between 18 and 65 years old undergoing elective bariatric surgery with general anesthesia; (3) Body mass index (BMI) >40 kg/m2 or BMI > 35 kg/m2 combined with one pre-existing disease; (4) Having signed the imformed consent.

Exclusion criteria

Exclusion criteria: (1) Obesity caused by endocrine diseases; (2) Combined with known drugs allergies associated with this study or severe cardiac,respiratory,renal, or hepatic disease; (3) With coagulation disorders; (4) Having conscious mental disorders ( possibly affecting pain intervention and evaluation).

Design outcomes

Primary

MeasureTime frame
pain level;emotion;cognition;memory;

Secondary

MeasureTime frame
blood pressure;heart rate;saturation of pulse oxygen;respiratory rate;blood gas analysis parameters;postoperative pain medication;expression levels of inflammatory cytokines in the blood;

Countries

China

Contacts

Public ContactYe ZHANG

The Second Hospital of Anhui Medical University

zhangye_hassan@sina.com+86 13966768081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 18, 2026