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The research of MRGPRX2 transcripts in peripheral blood basophil as a biomarker for perioperative period drug allergic reactions

The research of MRGPRX2 transcripts in peripheral blood basophil as a biomarker for perioperative period drug allergic reactions

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800019222
Enrollment
Unknown
Registered
2018-10-31
Start date
2017-10-11
Completion date
Unknown
Last updated
2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergy

Interventions

Gold Standard:Clinical outcome
Index test:MRGPRX2&#32
(Reverse&#32
Tran&#115
cription&#32
Polymerase&#32
Chain&#32
Reaction)

Sponsors

Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients had an operation during the sample period; 2. Aged 20 to 80 years.

Exclusion criteria

Exclusion criteria: 1. Patients whose transcript level of MRGPRX2 is lower than the limit of detection; 2. Woman who is pregnant; 3. Patient suffers with anaphylactoid reaction die in 24 hours; 4. Samples with inadequate information; 5. Samples which take or keep unproperly; 6. Samples been polluted; 7. Samples which fall to be detacted reasonably.

Design outcomes

Primary

MeasureTime frame
Sensitivity;specificity;Positive predictive value;Negative predictive value;—

Countries

China

Contacts

Public ContactLangchong He

Xi'an Jiaotong University

helc@mail.xjtu.edu.cn+86 029 82655392

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026