FindTrial
Sign In

A prospective randomized controlled trial for different maintaining doses of caffeine therapy for apnea of very low birthweight infants

A prospective randomized controlled trial for different maintaining doses of caffeine therapy for apnea of very low birthweight infants

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019204
Enrollment
Unknown
Registered
2018-10-31
Start date
2018-12-01
Completion date
Unknown
Last updated
2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Apnea of prematurity

Interventions

High-dose group:10mg/kg maintenance doses of caffeine
Low-dose group:5mg/kg 10mg/kg maintenance doses of caffeine

Sponsors

Tai'an Maternal and Child Health-Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. GA 28-32 weeks, birth weight<1500g; 2. Administration in NICU within 6 hours after birth; 3. Diagnose as AOP; 4. The guardians understand and voluntarily participate in the study and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Infants with severe asphyxia; 2. Birth with complex congenital malformations, chromosomal disorder or inherited metabolic diseases; 3. Giving up treatment and discharged from hospital;

Design outcomes

Primary

MeasureTime frame
Treatment efficiency;Duration of apnea;—

Secondary

MeasureTime frame
Duration of caffeine treatment;—

Countries

China

Contacts

Public ContactZhengying Yang

Tai'an Maternal and Child Health-Care Hospital

taian6621057@163.com+86 15662069959

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026