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Accurate diagnosis and treatment of Alzheimer's disease based on cerebral cortical neuromodulation

Accurate diagnosis and treatment of Alzheimer's disease based on cerebral cortical neuromodulation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800019199
Enrollment
Unknown
Registered
2018-10-31
Start date
2018-12-01
Completion date
Unknown
Last updated
2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's disease

Interventions

AD group:rTMS treatment
mild cognitive impairment :rTMS treatment
health control:N/A

Sponsors

The Shenzhen People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. early onset familial AD: younger than 65 years old, in line with NIA-AA AD diagnostic criteria, at least 2 first-degree relatives of at least 2 generations, 2-3 families; 2. sporadic AD: older than 65 Age, in line with NIA-AA AD diagnostic criteria, no family history, a total of 30 cases; 3. MCI: age is not limited, in line with NIA-AA MCI diagnostic criteria, no family history, a total of 30 cases; 4. normal controls: age greater than 65 years, no Cognitive function decreased, no neurodegenerative diseases or cerebral amyloid angiopathy, a total of 30 cases.

Exclusion criteria

Exclusion criteria: Dementia caused by vascular dementia, dementia with Lewy body, trauma, tumor, infection, thyroid dysfunction, vitamin B12 deficiency, alcohol and drug abuse.

Design outcomes

Primary

MeasureTime frame
neurological scale;eeg spectrum distribution;—

Countries

China

Contacts

Public ContactGuo Yi

The Shenzhen People's Hospital

xuanyi_guo@163.com+86 13902978692

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026