Prevention and treatment of bone and joint diseases by Chinese Medicine
Conditions
Interventions
Blood stasis NONFH:Drug intervention
Normal-constitution:Drug intervention
Unrelated relationship healthy volunteers:Drug intervention
Sponsors
Gansu Provincial Hospital of Traditional Chinese Medicine Ethics Committee
Eligibility
Sex/Gender
Male
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients with osteonecrosis of the femoral head who meet the diagnostic criteria of Chinese and Western Medicine (including surgery or traditional Chinese Medicine); The treatment person); 2. Aged 18~70 years old; 3. Exclude other serious diseases such as heart, brain and kidney; 4. Willing to accept this research investigator; 5. The retention of experimental specimens was approved by the patients or their families (signed informed consent).
Exclusion criteria
Exclusion criteria: 1. Diagnosed as traumatic osteonecrosis of the femoral head; 2. Pregnant or lactating women, who are allergic or unable to accept this treatment; 3. Rheumatoid arthritis, ankylosing spondylitis, dysplasia of the hip, etc; 4. Combined with severe visceral lesions or other serious metabolic abnormalities and bone tumors; 5. Patients with mental illness and mental retardation; 6. Patients who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| phosphatidylinositol-3-kinase, PI3K;protein kinase B, Akt;phosphatase and tensin homolog deleted on chromosome ten, PTEN;SH2-containing inositol 5-phosphatase 1, SHIP1;VEGF;P2Y12;miR-2;miR-155; | — |
Countries
China
Contacts
Public ContactLi Sheng-hua
Gansu Provincial Hospital of traditional Chinese Medicine
Outcome results
None listed