A multi-center study on adverse cardiovascular events influenced by sedation and anesthesia in elderly patients undergoing gastroscopy

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1800019093

Enrollment

Unknown

Registered

2018-10-25

Start date

2018-10-29

Completion date

Unknown

Last updated

2019-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Painless gastroscopy group:without

Common gastroscopic examination group:without

Eligibility

Sex/Gender

All

Age

70 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1) Patients aged between 70 and 90 years; 2) Patients who plan to undergo gastroscopic examination (including biopsy) or endoscopic polypectomy; 3) ASA grade II to III, normal cardiac function or grade I-II in NHYA cardiac function; 4) BMI is 18.5~29.9kg/m2 [BMI=body weight (Kg)/height (m)2] (American guidelines for controlling overweight and obesity in adults) 5) Patients who attend this study voluntarily and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1) Patients with severe nervous system disease(s) (such as acute stroke, convulsion and epilepsy that is not effectively controlled); 2) Patients whose blood pressure is no less than 180/110 mm Hg in pre-operative visit (i.e. hypertension in grade 3 based on WHO-ISH hypertension guideline); 3) Patients who had arrhythmia, unstable angina pectoris or myocardial infarction in recent 3 months 4) Patients with severe abnormality in renal or hepatic function 5)Patients who has difficult airway and severe respiratory tract disease (Obstructive sleep apnea syndrome, mouth opening disorder, limited neck or jaw movement, morbid obesity, acute respiratory infection, acute exacerbation of chronic obstructive pulmonary disease, uncontrolled asthma, etc.); 6) Patients with cardia Achalasia; 7) Patients with history of gastro-intestinal surgery; 8) Patients confirmed with or suspicious of abuse or prolonged use of anesthetic sedation or analgesia; 9) Patients treated with hormones or other immunosuppressive agents more than 10 days during past 6 months or complicated with immune disease; 10) Patients who have contraindications for are allergic to the tested drug and other narcotic drugs 11) Patients showing the oxygen saturation no more than 95% before the examination; 12) Patients who have participated other studies within past 30 days; 13) Patients with communication disorders.

Design outcomes

Primary

Measure	Time frame
Adverse Cardiovascular Events;	—

Secondary

Measure	Time frame
Breath;oxyhemoglobin saturation;degree of satisfaction;	—

Countries

China

Contacts

Public ContactMing Tian

Beijing Friendship Hospital Affiliated of Capital Medical University

13601167650@163.com+86 13601167650

Outcome results