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Endotype-driven prediction of acute exacerbations in chronic obstructive pulmonary disease (EndAECOPD)

Endotype-driven prediction of acute exacerbations in chronic obstructive pulmonary disease (EndAECOPD)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800019063
Enrollment
Unknown
Registered
2018-10-24
Start date
2018-12-01
Completion date
Unknown
Last updated
2019-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease (COPD)

Interventions

None listed

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Eligible participants are those aged between 40-80 years, confirmed COPD by 2018 Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria, and willing to write informed consent. Specifically, participants have been stable regarding their COPD in the past 2 months which is confirmed by the absence of hospitalizations, AND emergency visits, AND outpatient/community clinic visits, AND intravenous or oral administration of antibiotics and corticosteroids.

Exclusion criteria

Exclusion criteria: Patients with other respiratory diseases, a history of pneumonectomy, solid and hematological malignancy and severe organic diseases as well as psychiatric disorders will be excluded.

Design outcomes

Primary

MeasureTime frame
Exacerbation frequency;airway microbiota;

Secondary

MeasureTime frame
Pulmonary lung function;symptom score;sputum cytokines;bacterial load;single nucleotide polymorphisms;

Countries

China

Contacts

Public ContactJuanjuan Fu

West China Hospital, Sichuan University

fu.juanjuan@scu.edu.cn18980606822

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 20, 2026