Chronic obstructive pulmonary disease (COPD)
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Eligible participants are those aged between 40-80 years, confirmed COPD by 2018 Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria, and willing to write informed consent. Specifically, participants have been stable regarding their COPD in the past 2 months which is confirmed by the absence of hospitalizations, AND emergency visits, AND outpatient/community clinic visits, AND intravenous or oral administration of antibiotics and corticosteroids.
Exclusion criteria
Exclusion criteria: Patients with other respiratory diseases, a history of pneumonectomy, solid and hematological malignancy and severe organic diseases as well as psychiatric disorders will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exacerbation frequency;airway microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary lung function;symptom score;sputum cytokines;bacterial load;single nucleotide polymorphisms; | — |
Countries
China
Contacts
West China Hospital, Sichuan University