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Effect of enhanced external counterpulsation (EECP) on coronary microcirculation dysfunction (CMD) in patients with coronary heart disease and diabetes (EECP-CMD)

Effect of enhanced external counterpulsation (EECP) on coronary microcirculation dysfunction (CMD) in patients with coronary heart disease and diabetes (EECP-CMD)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800019060
Enrollment
Unknown
Registered
2018-10-24
Start date
2018-12-01
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease with diabetes

Interventions

Group 1:received a complete ECP course based on the second-stage preventive drug treatment for coronary heart disease
Group 2:only secondary prevention and treatment of coronary heart disease

Sponsors

The Eighth Affiliated Hospital, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 25-75 years old; 2. Coronary angiography shows that the coronary artery and the main branch have more than = 50% of the stenosis and implanted drug-eluting stent (DES); 3. Diagnosed diabetes patients; 4. Can accept and cooperate with more than half a year of follow-up; 5. Informed consent form approved by the Ethics Committee.

Exclusion criteria

Exclusion criteria: 1. Significant aortic regurgitation, aortic aneurysm, and dissection aneurysm; 2. Coronary artery spasm or severe coronary aneurysm; 3. Symptomatic congestive heart failure; 4. Heart valve disease, congenital heart disease, cardiomyopathy; 5. Cerebral hemorrhage within half a year, hemorrhagic disease or clear bleeding tendency; 6. Lower extremity infection, phlebitis, severe varicose veins, deep vein thrombosis; 7. Progressive malignancy or serious disease with poor prognosis; 8. Systolic blood pressure =180mmHg, or diastolic blood pressure =110mmHg when randomly grouped; 9. Severe arrhythmia affecting ECP therapy.

Design outcomes

Primary

MeasureTime frame
Differences in myocardial IMR values between the two groups after six months of stenting;

Secondary

MeasureTime frame
Differences in cardiac function (heart ultrasound) between the two groups after the stent;Differences in activity tolerance index between two groups of patients after stent operation;Differences in blood glucose between the two groups after six months of stenting;Differences in blood lipids between two groups of patients after six months of stenting;

Countries

China

Contacts

Public ContactJianwen Liang

The Eighth Affiliated Hospital, Sun Yat-sen University

tennic1982@163.com+86 13688847419

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026