mycoplasma pneumoniae pneumonia in children
Conditions
Interventions
double dose group:Jinzhen oral liquid (double dose of instruction) + Basic therapy (azithromycin)
original group:Jinzhen oral liquid (original dose of instruction) + Basic therapy (azithromycin)
placebo group:Jinzhen oral liquid placebo + Basic therapy (azithromycin)
Sponsors
First Teching Hospital of Tijianjin University of TCM
Eligibility
Sex/Gender
All
Age
2 Years to 13 Years
Inclusion criteria
Inclusion criteria: 1. Children meeting the diagnostic criteria of MPP and TCM syndrome differentiation; 2. Aged 2 to 13 years old; 3. Etiological diagnossis:detected mixed antibody of IgM and IgG in serum by PA,the single MP test antibody titer was greater than 1:160, or the single ELISA test of MP-IgM was positive; 4. Written ICF obtained from a legally acceptable representative or the child(=8 years old).
Exclusion criteria
Exclusion criteria: 1. Children meeting the diagnosis of severe CAP; 2. Children meeting the diagnosis of refractory MPP; 3. Children have some disease need to identify to MPP,such as tuberculosis, bacterial or viral pneumonia, hospital-acquired pneumonia, and other pathogenic microbial pneumonia; 4. Those who have underlying disease,such as primary immunodeficiency disease, acquired immunodeficiency syndrome, congenital respiratory tract malformation, pulmonary dysplasia, aspiration pneumonia, and pulmonary malignancies; 5. Children with severe malnutrition, rickets, and serious primary diseases of heart, brain, liver, kidney and hematopoiesis; 6. Children who was infection by mycoplasma pneumoniaewas in the last 3 months; 7. Allergic constitution ( for two or more substances allergies ) or the preparation of known composition allergies; 8. Those who are not included based on the investigators judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of clinical recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| antipyretic time;Relieving time of cough and expectoration;Ratio of transfer to severe CAP or refractory MPP;Effective rate of Chest x-rays;Effects of TCM symptoms; | — |
Countries
Chian
Contacts
Public ContactLi Xinming
The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed