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Evaluating the role of corticostriatal pathway in anhedonia patients by transcranial repetitive magnetic stimulation (rTMS) activating the orbital frontal cortex (OFC)

Evaluating the role of corticostriatal pathway in anhedonia patients by transcranial repetitive magnetic stimulation (rTMS) activating the orbital frontal cortex (OFC)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018997
Enrollment
Unknown
Registered
2018-10-20
Start date
2018-11-01
Completion date
Unknown
Last updated
2018-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anhedonia

Interventions

rTMS:rTMS stimulate OFC
shame rTMS:shame rTMS stimulate OFC

Sponsors

Nanfang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Anhedonia patient, SHAPS score >=20 patients; 2. aged 18-60 years old; 3. Those who have stopped taking drugs or whose condition is stable and do not change the current psychiatric drugs, they willing to use rTMS to improve the anhedonia.

Exclusion criteria

Exclusion criteria: 1. patients with drug abuse or drug dependence; 2. patients with epilepsy, unstable or untreated severe somatic diseases; 3. currently in mania, mental symptoms and suicidal tendencies; 4. there is a history of mental retardation, autism, attention and hyperactivity disorder, and difficulty in reading and writing; 5. pregnant women or women of childbearing age who are going to pregnant; 6. change of medication and dosage change 2 weeks before the start of the trial.

Design outcomes

Primary

MeasureTime frame
Snaith-Hamilton Pleasure Scale;Temporal Experience of Pleasure Scales;

Countries

China

Contacts

Public ContactMeilei Su

NanFang Hospital, Southern Medical University

sumeilei@126.com+86 020-61642066

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026