Eye Fatigue
Conditions
Interventions
Low Dose of LEZ Group:orally receive LEZ containg 6 mg of lutein once daily
Midium Dose of LEZ Group:orally receive LEZ containg 10 mg of lutein once daily
High Dose of LEZ Group:orally receive LEZ containg 14 mg of lutein once daily
Placebo Group:orally receive placebo once daily
Sponsors
Xin Hua Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years; 2. Do extended near work each day with eye strain or tired eyes; 3. Signed informed consent obtained for participating the study.
Exclusion criteria
Exclusion criteria: 1. Subject has infectious or traumatic eye diseases or had an eye surgery within 3 months; 2. Subject has either internal or external eye diseases with cornea, lens, vitreous body, and fundus lesions, and etc.; 3. Subject has disease of cardiovascular, cerebrovascular, liver, kidney, hematopoietic system and other diseases; 4. Subject is pregnant or lactating, or has an allergy; 5. Subject currently takes any drugs or food supplement related to the study product in recent days, which interferes with the study product; 6. Subject currently takes drugs, nutrition supplements or on any therapy for the treatment of eye disease for a long period of time and not willing to discontinue them; 7. Subject participated another clinical trial in the past three months; 8. Subject is not willing to comply the study procedures; 9. Subject has any diseases that can affect the evaluation of the study product; 10. Subject takes any drugs that can affect the evaluation of the study product.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Macular Pigment Optical Density;Visual Fatigue Symptom Evaluation;Visuognosis Persistence;Schirmer test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Vision test;Optical Coherence Tomography;Body composition analysis;Food frequency questionnaire;Routine blood test;Urinalysis;Kidney function test;Liver function test;Blood lipid profile; | — |
Countries
China
Contacts
Public ContactJuntao Kan
Amway (China) R&D Center
Outcome results
None listed