stroke
Conditions
Interventions
Group 2:Routine treatment + High-frequency rTMS
Sponsors
Nanjing First Hospital Nanjing Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. First onset, duration of 24 hours to 6 weeks, the general situation is stable, confirmed by magnetic resonance DWI acute onset, and for subcortical ischemic stroke patients; 2. Hemiplegic patients with upper extremity hand dysfunction were classified as hemiplegic patients according to the functional classification of hemiplegic hand (hemiplegic hand function assessment included five practical hand functions for daily life, and patients with complete hemiplegia who could complete at least one of these five functions were hemiplegic patients with complete hand function. Part of hemiplegia patients, and the duration is longer than 48 hours; 3. The patients in the study group were clear-minded, without obvious speech cognitive impairment (MMSE < 22), and could cooperate with MRI examination; 4. there were no long-term alcoholism and long-term use of CNS drugs; 5. of the patients were 30-65 years old and volunteered for the trial.
Exclusion criteria
Exclusion criteria: 1. with severe heart disease or severe physical illness; 2. intracranial metal implanted implants, magnetic materials, pacemakers or skull defects; 3. intracranial hypertension; 4. persons or family history of epilepsy or mental illness; 5. the history of drugs used to alter cortical excitability (sedation and antidepressants): 6. pregnant women; 7. researchers believe that those who do not conform to the inclusion criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Upper Extremity Fugl-Meyer Assessment;Wolf Motor Function Test ,;FTHUE-HK;VBM;rs-fMRI;Diffusion Tensor imaging; | — |
Contacts
Public ContactTing Yang
Nanjing First Hospital Nanjing Medical University
Outcome results
None listed