Epilepsy
Conditions
Interventions
Male group:rocuronium
Female group:rocuronium
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for elective neurosurgery under general anesthesia; 2. Aged 18-59 years; 3. BMI 18.5-24.0 kg/m2; 4. ASA grade II or III; 5. History of epilepsy of more than one year. 6. Oral single antiepileptic drug at most before operation
Exclusion criteria
Exclusion criteria: Patients with neuromuscular disease, history of endocrine disease, hypoproteinemia, electrolyte disorders, acid-base imbalance, arrhythmia, difficult airway, abnormal liver and kidney function, allergic history, and recently taking drugs that affect the function of neuromuscular junctions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Onset time of rocuronium;Peak time of rocuronium;Different recovery time of rocuronium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intubation conditions;Serum concentration of rocuronium;Rocuronium consumption per unit time body weight; | — |
Countries
China
Contacts
Public ContactHan Mingming
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed