Type 2 Diabetes Mellitus
Conditions
Interventions
one:take hypoglycemic agents orally
two:inject insulin
three:take hypoglycemic agents orally and inject insulin
Sponsors
Nanshan Affiliated Hospital of Shenzhen University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: All type 2 diabetic patients meet the standard of the diagnosis and classification of type 2 diabetic, which made by the WHO in 1999. Aged between 18 and 65 years, have lived in the area at least 5 years, HBA1C = 7%, FPG =7.0mmol/l and/or 2hPG =11.1mmol/l,without severe acute or chronic complications of diabetes.
Exclusion criteria
Exclusion criteria: The exclusion criteria included having such diseases in the last 6 months: 1. Hematological diseases; 2. Cancer and other chronic wasting diseases such as tuberculosis and thyroidism; 3. Infectious diseases; 4. Liver disease or transaminases increased for more than 3 times; 5. Kidney disease (creatinine=1.5mg/dl) or rheumatoid arthritis; 6. Valve replacement, cardiac function class III or above according to the NYHA; 7. Bleeding history, blood donation or blood transfusion within 4 months; 8. Smokers; 9. Impaired pulmonary function; 10. Pregnancy; 11. Application of drug which could affect the lifespan of RBC, such as ribavirin, barbital or phenobarbitone sodium. Women patients should avoid the menstrual period when monitoring RBC lifespan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting blood glucose;glycosylated hemoglobin;red blood cells count;Red blood cell deformability;hematocrit;triglyceride;total cholesterol;high density lipoprotein choleste;low density lipoprotein choleste;alanine aminotransferase;aspartate aminotransferase;serum creatinine (Cr);hemoglobin;blood sugar;fructosamine;Urinary protein; | — |
Countries
China
Contacts
Public ContactZhenhe Huang
Nanshan Affiliated Hospital of Shenzhen University
Outcome results
None listed