Peri-implantitis
Conditions
Interventions
Experimental Group:Mechanical debridement+photodynamic therapy
Sponsors
Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Male or female aged 18 to 80 years; (2) Patients are diagnosed as peri-implantitis; (3) Periodontal probing depth = 4 mm for at least 1 implant; (4) The plaque index = 2 points around the implant; (5) Bleeding happens after probing of the mucosa around the implant, and the sulcus bleeding index is = 2 points; (6) Periodontal attachment loss = 2.5 mm; (7) Pateients can understand and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with oral diseases/stomatological allergies on screening; (2) Antibiotics or non-steroidal anti-inflammatory drugs have been used within 3 months before diagnosis; (3) Patients who have been planted and repaired within one year; (4) Patients who have a history of alcohol abuse or drug abuse; (5) Long-term smokers; (6) Patients with implant loosening; (7) Patients whose ALT and / or AST are more than 1.5 times the upper limit of the normal value of our center, or the serum creatinine exceeds the upper limit of the normal value of our center; (8) Patients who have participated in other drug clinical trials within three months; (9) Pregnant or lactating women, or patients who have a pregnancy plan within a year; (10) Patients with a history of immunosuppressive diseases (such as history of HIV infection), a history of malignant tumors, a history of autoimmune diseases, a history of tuberculosis, a cardiovascular insufficiency, or a serious illness of other organ systems judged by the investigator; Any other circumstances that the investigators judge are not suitable for the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing depth;Adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Plaque index around the implants;Sulcus bleeding index;Periodontal attachment loss; | — |
Countries
China
Contacts
Public ContactZuomin Wang
Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
Outcome results
None listed