FindTrial
Sign In

Safety assessment of gene therapy in major genetic related diseases

Evaluating the safety of genome editing in abandoned human embryos and in monkey and mouse embryos

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018955
Enrollment
Unknown
Registered
2018-10-18
Start date
2017-04-01
Completion date
Unknown
Last updated
2018-11-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major genetic disease

Interventions

A:Cas9 RNA
B:Cas9 Protein

Sponsors

South University of Science and Technology of China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Infertility caused by female fallopian tube obstruction; 2. aged 23 to 43 years old; 3. no drug treatment affecting endocrine function within 3 months; 4. the couple to participate voluntarily; 5. long-term ovulation promotion program was used;

Exclusion criteria

Exclusion criteria: 1. Patients with severe physical or mental illness (including malignant tumors); 2. denied to participate after explanation by the project team members; 3. patients with endocrine-related diseases that affect the accurate determination of hormone levels.

Design outcomes

Primary

MeasureTime frame
On target rate;off target;—

Countries

China

Contacts

Public ContactHe Jiankui

Third Affiliated Hospital of Shenzhen University

hejk@sustc.edu.cn+86 18688955436

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026