A study for brain network features on monozygotic twins with autism spectrum disorder

Status

Recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1800018953

Enrollment

Unknown

Registered

2018-10-18

Start date

2018-11-01

Completion date

Unknown

Last updated

2018-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism spectrum disorder

Interventions

Case series:Nil

Eligibility

Sex/Gender

All

Age

3 Years to 10 Years

Inclusion criteria

Inclusion criteria: 1. monozygotic twins; 2. aged 3~10 years old; 3. One of the twins is fully compliant with another based on DSM-5 diagnostic criteria for ASD; or both are fully compliant with the DSM-5 for ASD diagnostic criteria; 4. Used to the right hand; 5. The guardian agreed to participate in the study.

Exclusion criteria

Exclusion criteria: 1. Although it meets the clinical diagnostic criteria of ASD, there are secondary ASDs with clear etiological diagnosis, such as: fragile X syndrome, tuberous sclerosis, propiophenone Urine, Rett syndrome, angel syndrome, pediatric giant brain malformation syndrome, type 1 neurofibromatosis, Zhubert syndrome, Smith-Lemli-Opitz syndrome, etc.; 2. a clear history of traumatic brain injury; 3. have a history of nervous system diseases and serious physical diseases; 4. There are clear mental disorders of children with attention deficit hyperactivity disorder and learning disabilities; 5. people taking psychotropic drugs within two weeks.

Design outcomes

Primary

Measure	Time frame
volume;FA;Reho;FC;	—

Countries

China

Contacts

Public ContactXiaoyan Ke

Nanjing Brain Hospital Affliated to Nanjing Medical University

kexynj@hotmail.com+86 13305176562

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026