anesthesia of hip surgery
Conditions
Interventions
C:Combined of general anesthesia and nerve blockade
N:Nerve blockade
Sponsors
Shanghai Jiaotong University affiliated 6th Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. aged at least 65 years male and female; 2. surgery at 24-72 hours after hip fracture; 3. BMI 18 to 30; 4. ASA Physical Status Classification: class I to class III; 5. CRAMS scale 9 to 10.
Exclusion criteria
Exclusion criteria: 1. Injured less than 24 hours or more than 72 hours 2. ASA Physical Status Classification: class IV and class V; 3. CRAMS scale less than 9; 4. Patients with multiple injuries; 5. With a history of chronic immune system diseases; 6. With a history of prosthesis implantation; 7. Being or with a history of immunocompromised drugs taken in 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Th1/Th2 cells ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| Peripheral blood T cell subgroup level;Peripheral blood lymphocyte level;Plasma cytokine levels;Incidence of postoperative infection;Incidence of organ dysfunction;Inpatient days;Death rate; | — |
Countries
China
Contacts
Public ContactJiawei Shang
Shanghai Jiaotong University Affiliated 6th Hospital
Outcome results
None listed