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Clinical randomized, double-blind, placebo-controlled trial for the effect of Bifidobacterium lactis M8 on protein-bound toxins and intestinal flora in maintenance hemodialysis patients

Clinical randomized, double-blind, placebo-controlled trial for the effect of Bifidobacterium lactis M8 on protein-bound toxins and intestinal flora in maintenance hemodialysis patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018932
Enrollment
Unknown
Registered
2018-10-17
Start date
2018-10-31
Completion date
Unknown
Last updated
2018-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Maintenance hemodialysis for end-stage renal disease

Interventions

Sponsors

Weihai Municipal Hospital of Shandong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years old; 2. Meet the MHD standard; 3. Can standardize the treatment of dialysis, the condition is relatively stable, and the complications and comorbid drugs can be controlled; 4. Informed and voluntarily participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Surgical patients within 1 month; 2. Patients with fractures or trauma within 3 months; 3. Patients with unstable vital signs and unstable conditions; 4. Patients with severe heart failure and other critical conditions need to continue bedside hemofiltration treatment; 5. Combined with active primary malignant tumors, stroke, myocardial infarction and other serious primary diseases; 6. Patients with gastrointestinal diseases such as gastrointestinal bleeding, irritable bowel syndrome, Crohn's disease or ulcerative colitis, and patients with a history of gastrointestinal surgery; 7. Patients with a history of mental illness; 8. Patients with a history of kidney transplantation or who are scheduled to undergo a kidney transplant within 3 months; 9. Take antibiotics, glucocorticoids or other immunosuppressive agents, foods containing probiotics, prebiotics, medicines, etc. within one month; 10. Those who are allergic to the test sample or have obvious gastrointestinal symptoms such as intolerance; 11. Accept other clinical trial patients at the same time; 12. The researcher determined that the researcher could not complete the research on time...

Design outcomes

Primary

MeasureTime frame
Protein binding toxin;Intestinal flora;

Countries

China

Contacts

Public ContactYun Geng

Weihai Municipal Hospital of Shandong

gengyunkt2010@163.com+86 18660377086

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026