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Effect of intravenous lidocaine on intrapulmonary shunt and oxygenation during one-lung ventilation

Effect of intravenous lidocaine on intrapulmonary shunt and oxygenation during one-lung ventilation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018928
Enrollment
Unknown
Registered
2018-10-17
Start date
2018-10-16
Completion date
Unknown
Last updated
2018-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrapulmonary shunt

Interventions

Group 1:Single intravenous lidocaine
Group 2:Intraoperative continuous intravenous pumping of lidocaine
Group C (Control group):nothing

Sponsors

Yangzhou First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with single-lung ventilation undergoing lobectomy or esophageal surgery, aged 20-65 years, BMI 18~25kg/m2, ASA I or II

Exclusion criteria

Exclusion criteria: Preoperatively combined with severe cardiovascular, liver, kidney and other important organ diseases, moderate anemia, pulmonary function tests more than moderate abnormalities, FEV1/FVC <65% (pulmonary function test: record FVC%, FEV1%), long-term Use sedative analgesics, hypoproteinemia, water and electrolytes, and acid-base balance disorders and patients with coagulopathy.

Design outcomes

Primary

MeasureTime frame
SpO2;Hb;PaCO2;PvO2;PaO2;SaO2;SvO2;TNF-a;IL-6;IL-8;MAP;HR;—

Countries

China

Contacts

Public ContactDawei Yang

Yangzhou First People's Hospital

yangdawei307@163.com+86 13773531263

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026