Effect of multimodal TMS on swallowing function in patients with cognitive-swallow disorder after acquired brain injury

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1800018926

Enrollment

Unknown

Registered

2018-10-17

Start date

2019-01-01

Completion date

Unknown

Last updated

2018-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acquired brain injury

Interventions

Team A:rTMS intervention in swallowing function network (motor area of affected side)

Team B:rTMS on Cognitive Central Nervous Function Area (Left dorsolateral prefrontal)

Team C:sham rTMS

Eligibility

Sex/Gender

All

Age

50 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with acquired brain injury (cerebral infarction or cerebral hemorrhage, brain trauma), including stroke patients meet the 2007 WHO diagnostic criteria for stroke; Confirmed by CT/MRI as acquired brain injury; 2. MoCA score < 26 points; 3. No history of mental or neurological disease; 4. aged 50-75 years; 5. Diagnosed with swallowdisorder by EAT-10 and VFSS; 6. The patient can receive oral feeding though adjust food in VFSS.

Exclusion criteria

Exclusion criteria: 1. Patient with a history of head and neck radiotherapy or oral surgery, or other peripheral neuromuscular diseases caused by impaired swallowing function; 2. Patient with tongue muscle atrophy or taste disorders; 3. Patient with sensory aphasia or complete aphasia; 4. Patient with previous history of epilepsy; 5. Those who refuse to sign the informed consent form.

Design outcomes

Primary

Measure	Time frame
videofluoroscopic swallowing study;	—

Countries

China

Contacts

Public ContactWang Yujue

Fifth Affiliated Hospital of Guangzhou Medical University

wangyj43@foxmail.com+86 13422049798

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026