colorectal neoplasms
Conditions
Interventions
TAPB:continue TAPB perioperaitive
The flurbiprofen group:Continuous infusion of flurbiprofen by postoperative analgesic pump
TAPB+flurbiprofen group:Continuous intraoperative and postoperative TAPB and continuous intravenous analgesic pump infusion of flurbiprofen
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 65 to 80 years male and female; 2. Surgery for colorectal neoplasms to be performed within a prescribed period; 3. One or more of the common diseases of old age, such as hypertension, heart disease and diabetes.
Exclusion criteria
Exclusion criteria: 1. Patients and their family members refuse to accept the clinical trial; 2. Complicated with acute cholangitis, gastrointestinal bleeding or ascites, etc.; 3. Hepatic encephalopathy, psychosis or neuropathy; 4. Body weight for acid-base and electrolyte imbalances, endotoxemia, and cachexia decreased by more than 2% or 5% in the past 2 months or 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of chronic pain after operation;Incidence of postoperative cognitive dysfunction; | — |
Countries
China
Contacts
Public ContactLIU YI
Chinese PLA General Hospital
Outcome results
None listed