Genital Chlamydia trachomatis infections
Conditions
Interventions
Group B:Conventional doxycycline regimen:100 mg orally twice daily for 7 days
Sponsors
Shenzhen Nanshan Center for Chronic Disease Control
Eligibility
Sex/Gender
Female
Age
20 Years to 49 Years
Inclusion criteria
Inclusion criteria: To be eligible for participating the study, the following criteria should be met: 1. Above 18 years of age, male or female; 2. Adequate comprehension skills to give informed consent; 3. Able to attend weekly follow-up visits and specimen collection at the study clinic for 4 weeks; 4. Commitment to have not sexual behaviors for the next 4 weeks after initiating treatment.
Exclusion criteria
Exclusion criteria: The women who meet any of the following criteria should be excluded from participation in the study: 1.Pregnant or lactating condition; 2.Current commercial sex work; 3.Current infection detected as a part of a routine test for re-infection; 4.Concomitant infection with Neisseria gonorrhoeae; 5.Concurrent PID or Epididymitis ; 6.HIV positive status; 7.History of cardiovascular conditions and current use of QT-prolonging drugs; 8.Known allergy to macrolides and/or tetracyclines; 9.Self-report of antibiotic use in the last 3 weeks; 10.Unwillingness to participate in the study or provide informed consent; 11.Unwillingness to attend weekly visits for at least 4 weeks at the study clinic; 12.Not being reached by a mobile phone in the next 4 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CT DNA in first-catch urine sample or cervical swab sample; | — |
Secondary
| Measure | Time frame |
|---|---|
| CT RNA in first-catch urine sample or cervical swab sample; | — |
Countries
China
Contacts
Public ContactChen Xiang-sheng & Luo Zhen-zhou
Institute of Dermatology and Hospital for Skin Diseases, Chinese Academy of Medical Sciences & Peking Union Medical Collage
Outcome results
None listed