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Microbiological metabolomics of fecal samples in colorectal cancer patients

Using microbiological metabolomic methods to screen biomarkers of chemotherapy-associated diarrhea in advanced colorectal cancer treated with FOLFIRI regimen

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800018908
Enrollment
Unknown
Registered
2018-10-16
Start date
2019-01-01
Completion date
Unknown
Last updated
2018-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer

Interventions

Diarrhea group:FOLFIRI regimen
Control group:No

Sponsors

Huzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Cancer was confirmed by pathological examination and volunteered to participate in the study; 2. Patients voluntarily accepted chemotherapy; 3. Join in this research project voluntarily.

Exclusion criteria

Exclusion criteria: 1. Patients with diarrhea before chemotherapy; 2. Terminate chemotherapy because of progression of disease and side effects; 3. accepted neo-adjuvant chemotherapy; 4. could not obtained the stool samples; 5. used oral probiotics before chemotherapy.

Design outcomes

Primary

MeasureTime frame
Microorganisms and metabolites;—

Countries

China

Contacts

Public ContactHan Shuwen

Huzhou Central Hospital

shuwenhan985@163.com+86 18768233016

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026