Primary liver cancer
Conditions
Interventions
Group 1:DEB-tace
Group 2:C-tace
observation group:none
Sponsors
Qilu Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) patients aged 18 years and older with primary liver cancer (-80) are expected to have a survival period of at least 3 months; (2) no portal vein main stem tumor thrombus; (3) Child-Pugh grade of liver function was A or B grade; ECOG physical condition 2 scores; (4) no bleeding tendency, normal coagulation function or coagulation dysfunction can be corrected by treatment; (5) white blood cell count is more than 3 x 10^9/L; (6) hemoglobin is more than 8.5g/dl; (7) platelet count is more than 50 x 10^9/L; (8) Prothrombin time international standardized ratio (INR) <= 2.3 or prothrombin time (PT) does not exceed the normal control upper limit of 3 seconds. serum creatinine is less than 1.5 times of the upper limit; (9) the patients and / or their family members agreed to join the clinical trial and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) diffuse liver cancer; (2) combined with portal vein cancer thrombus; (3) combined hepatic vein tumor thrombus; (4) combined with lymph node metastasis and extrahepatic distant metastasis; (5) the grade of liver function is Child-Pugh C grade, which can not be improved by liver protection; (6) uncorrected coagulation dysfunction and obvious hemogram abnormalities with obvious bleeding tendency; (7) refractory massive ascites; (8) ECOG physical fitness score was<2; (9) active infection, especially bile duct inflammation; (10) serious heart, lung, kidney and brain diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFS; | — |
Countries
China
Contacts
Public ContactZhang Kai
Qilu Hosptial of Shandong University
Outcome results
None listed